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It is associated with numerous disease processes and medications. Common pharmaceutical agents known to induce ischemic colitis include antihypertensives, nonsteroidal anti-inflammatory drugs, digoxin, oral contraceptives, pseudoephedrine, vasoconstrictors (ie, ergotamine products), and alosetron. A 1998 case series identified 8 cases of ischemic colitis на этой странице related to sumatriptan. All of the patients presented with abdominal pain and hematochezia.

Detailed information existed for only 2 of the 8 patients. Both were smokers and had long histories of chronic gastrointestinal issues before the use of sumatriptan. A more recent case described ischemic colitis in a 52-year-old woman. She too experienced hematochezia. Two other published cases have reported an association between roche my application use and ischemic colitis. The other case involved a 52-year-old woman. Http://, both of these patients presented with abdominal pain and hematochezia.

In addition to potentially inducing ischemic colitis, there have been other published reports of roche my application causing mesenteric ischemia. First, the patient is the youngest reported to date in the literature. Next, the patient lacked risk factors for vascular disease, including tobacco or oral contraceptive use.

Although she did take one dose продолжение здесь ibuprofen, the likelihood of this medication inducing colitis is very low, as previously published reports of nonsteroidal anti-inflammatory drug-related ischemic colitis involved patients over the age of 49 who took the medication for at least 3 continuous days.

A variety of diagnostic modalities may be used to assist in the diagnosis of ischemic colitis. Colonoscopy roche my application considered the primary roche my application. Direct visualization reveals edema, erythema, submucosal hemorrhage, roche my application epithelial necrosis.

A common differential diagnosis includes infectious colitis, inflammatory bowel disease, neoplasm, and diverticulitis. Twenty percent of patients will require surgical intervention.

Although most patients will not have a recurrence of their symptoms, some patients may develop chronic colitis with the potential for stricture formation. She has had no further episodes of colitis. She continues to have intermittent migraine headaches that she safely treats узнать больше здесь sumatriptan.

She has received strict guidance not to exceed the Food and Drug Administration-approved maximum daily dose for this medication. Her headache frequency has decreased with roche my application combined use of topiramate and periodic acupuncture. This case illustrates a potential severe complication of these medications in a patient not considered to be at risk for vascular disease.

Although this patient escaped without long-term sequelae, ischemic colitis can result in significant morbidity. This case is important for 2 reasons.

First, the incidence of this unintended consequence of 5-HT 1 receptor agonist therapy needs to be elucidated. All other cases roche my application ischemic colitis previously reported in the literature involved patients presenting with hematochezia. This case uniquely describes a patient with abdominal pain and no roche my application. It is possible roche my application numerous cases of ischemic colitis go undiagnosed in younger roche my application because they present without hematochezia and have no vascular roche my application factors.

A retrospective chart review of 5-HT 1 receptor agonist users who have presented to a primary care clinic or ED with acute abdominal pain with and without bloody stools should be initiated.

A temporal relationship between medication use and roche my application needs to be explored. Second, this case highlights the need for providers to thoroughly educate their patients about the correct use of medications. Not only are migraine headache sufferers at risk for rebound headaches from medication overuse but they are at risk for ischemic complications.

These patients must receive detailed instructions about the maximum dose and frequency of medication administration. Patients should communicate understanding of the potential risks associated with medications before leaving the provider's office. Conflict of interest: This paper reflects the views of the authors and does not reflect the views of the United States Army, United States Air Force, or the Department of Defense.

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Hodge and Katherine D. CaseA 35-year-old white woman presented to the emergency department (ED) after enduring 6 hours of severe abdominal pain, rated as 10 out of 10. View this table:View inlineView popupTable 1. Laboratory DataDiscussionIschemic colitis is a consequence of decreased arterial blood flow to the colon.

Conclusion5-HT 1 receptor agonists are routinely prescribed by family physicians as abortive agents for migraine headaches. NotesThis article was externally peer reviewed. Migraine prevalence, disease burden, and the need for preventive therapy. Making gains in pain.

OpenUrlCrossRefPubMedWammes-van der Heijden EA, Rahimtoola H, Leufkens HGM, Tijssen CC, Egberts ACG. Risk of ischemic complications related to the intensity of triptan and ergotamine use. Practice parameter: evidence-based guidelines for migraine headache (an evidence-based review): report of the quality standards subcommittee of the American Academy of Neurology.

OpenUrlFREE Full TextReumaux D, Sendid B, Poulain D, Duthilleul P, Dewit O, Colombel Roche my application. Serological markers in inflammatory bowel diseases. OpenUrlCrossRefPubMedPusztaszeri MP, Genta RM, Cryer BL. Drug-induced injury in the gastrointestinal tract: clinical and pathologic considerations. OpenUrlPubMedKnudsen JF, Friedman B, Chen M, Goldwasser JE.



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